JCOG9907
Regimen
- Experimental
- preoperative cisplatin/5-FU x2 followed by surgery
- Control
- surgery followed by postoperative cisplatin/5-FU x2
Population
Stage II/III (excluding T4) thoracic ESCC
Key finding
5y OS 55% (preop CF) vs 43% (postop CF); HR 0.73, P=0.04. Preoperative CF > postoperative CF.
Source: PMID 21879261