PALACE-1

NCT03792347 📎

Regimen

Experimental
preoperative pembrolizumab + carboplatin/paclitaxel + 41.4 Gy RT

Population

Resectable ESCC, any PD-L1 status

Key finding

pCR 55.6% (10/18 resected); G3+ AEs 65% (lymphopenia most common); no surgical delay; one treatment-related death (grade V AE).

Source: PMID 33373868

Timeline