TIME
Regimen
- Experimental
- minimally invasive esophagectomy (MIE)
- Control
- open transthoracic esophagectomy
Population
Resectable esophageal or GEJ cancer, age 18-75
Key finding
In-hospital pulmonary infection 34% (open) vs 12% (MIE), RR 0.35, P=0.005. 2-week pulmonary infection 29% vs 9%, P=0.005.
Source: PMID 22552194
Timeline
Guideline citations
- NCCN ESOPHAGEAL (p.50)