CRITICS
Regimen
- Experimental
- preoperative chemotherapy + postoperative chemoradiotherapy (45 Gy + capecitabine/cisplatin)
- Control
- perioperative chemotherapy (ECC or EOC)
Population
Stage IB-IVA resectable gastric/GEJ cancer
Key finding
mOS 43 vs 37 mo (HR 1.01, 95% CI 0.84-1.22, p=0.90); 5y OS similar; postop compliance 59%/62%
Source: PMID 29650363
Timeline
Guideline citations
- NCCN GASTRIC (p.88)
- CSCO GASTRIC 2025 (p.65)⚠️ OCR source