FLOT4
Regimen
- Experimental
- perioperative FLOT x4+4 cycles
- Control
- perioperative ECF or ECX x3+3 cycles
Population
Locally advanced resectable gastric/GEJ adenocarcinoma (cT2+ or cN+)
Key finding
mOS 50 vs 35 mo (HR 0.77, 95% CI 0.63-0.94); pCR 16% vs 6%
Source: PMID 30982686
Timeline
Guideline citations
- NCCN GASTRIC (p.38)
- CSCO GASTRIC 2025 (p.62)⚠️ OCR source