MAGIC
Regimen
- Experimental
- perioperative ECF (3 preop + 3 postop cycles) + surgery
- Control
- surgery alone
Population
Resectable adenocarcinoma of stomach, EGJ, or lower esophagus
Key finding
5y OS 36% vs 23% (HR 0.75, 95% CI 0.60-0.93, P=0.009); PFS HR 0.66 (95% CI 0.53-0.81, P<0.001)
Source: PMID 16822992
Timeline
Guideline citations
- NCCN GASTRIC (p.77)
- CSCO GASTRIC 2025 (p.63)⚠️ OCR source