CODEBREAK-200

NCT04303780 📎

Regimen

Experimental
sotorasib
Control
docetaxel

Population

KRAS G12C NSCLC post-platinum+IO

Key finding

mPFS 5.6 vs 4.5 mo, HR 0.66 (0.51-0.86); OS neutral; confirmatory RCT

Source: PMID 36764316

Timeline

  • Enrollment start: 2020-06-04 📎

Guideline citations

  • NCCN NSCLC Version 5.2026 (p.206)
  • CSCO NSCLC 2025 ⚠️ OCR source