DESTINY-LUNG01
Regimen
- Experimental
- T-DXd 6.4 mg/kg
- Control
- none
Population
HER2-mut pre-treated NSCLC
Key finding
ORR 55% (44-65); mDOR 9.3 mo; mPFS 8.2 mo; first HER2-targeted ADC efficacy in NSCLC
Source: PMID 34534430
Timeline
- Enrollment start: 2018-05-21 📎
Guideline citations
- NCCN NSCLC Version 5.2026 (p.113)
- CSCO NSCLC 2025 ⚠️ OCR source