FLAURA2

NCT04035486 📎

Regimen

Experimental
osimertinib + platinum+pemetrexed
Control
osimertinib

Population

Advanced EGFR-mut NSCLC, chemo-naive

Key finding

mPFS 25.5 vs 16.7 mo, HR 0.62 (0.49-0.79); TKI+chemo 可作为高危选项

Source: PMID 37937763

Timeline

  • Enrollment start: 2019-07-02 📎

Guideline citations

  • NCCN NSCLC Version 5.2026 (p.201)
  • CSCO NSCLC 2025 ⚠️ OCR source