IMPOWER150

NCT02366143 📎

Regimen

Experimental
atezolizumab + bevacizumab + carbo + paclitaxel
Control
bev + carbo + paclitaxel

Population

1L non-sq NSCLC incl. EGFR/ALK after TKI failure

Key finding

ABCP vs BCP PFS HR 0.62 (0.52-0.74); mOS 19.2 vs 14.7 mo HR 0.78 (0.64-0.96)

Source: PMID 29863955

Timeline

  • Enrollment start: 2015-03-31 📎

Guideline citations

  • NCCN NSCLC Version 5.2026 (p.174)
  • CSCO NSCLC 2025 ⚠️ OCR source